374 research outputs found
Microscopic study of CaCa fusion
We investigate the fusion barriers for reactions involving Ca isotopes
, , and
using the microscopic time-dependent
Hartree-Fock theory coupled with a density constraint. In this formalism the
fusion barriers are directly obtained from TDHF dynamics. We also study the
excitation of the pre-equilibrium GDR for the
system and the associated -ray
emission spectrum. Fusion cross-sections are calculated using the incoming-wave
boundary condition approach. We examine the dependence of fusion barriers on
collision energy as well as on the different parametrizations of the Skyrme
interaction.Comment: 11 pages, 13 figure
Microscopic Calculation of Fusion: Light to Heavy Systems
The density-constrained time-dependent Hartree-Fock (DC-TDHF) theory is a
fully microscopic approach for calculating heavy-ion interaction potentials and
fusion cross sections below and above the fusion barrier. We discuss recent
applications of DC-TDHF method to fusion of light and heavy neutron-rich
systems.Comment: 8 pages, 8 figure
Fusion using time-dependent density-constrained DFT
We present results for calculating fusion cross-sections using a new
microscopic approach based on a time-dependent density-constrained DFT
calculations. The theory is implemented by using densities and other
information obtained from TDDFT time-evolution of the nuclear system as
constraint on the density for DFT calculations.Comment: 4 Pages, 6 Figures Proceedings of INPC 2013, to be published in EPJ
Web of Conference
Microscopic DC-TDHF study of heavy-ion potentials and fusion cross sections
We study heavy-ion fusion reactions at energies near the Coulomb barrier, in
particular with neutron-rich radioactive ion beams. Dynamic microscopic
calculations are carried out on a three-dimensional lattice using the
Density-Constrained Time-Dependent Hartree-Fock (DC-TDHF) method. New results
are presented for the Sn+Ca system which are compared to
Sn+Ca studied earlier. Our theoretical fusion cross-sections
agree surprisingly well with recent data measured at HRIBF. We also study the
near- and sub-barrier fusion of O on C which is important to
determine the composition and heating of the crust of accreting neutron stars.Comment: Talk given by . Volker E. Oberacker at the 11th International
Conference on Nucleus-Nucleus Collisions (NN2012), San Antonio, Texas, USA,
May 27-June 1, 2012. To appear in the NN2012 Proceedings in Journal of
Physics: Conference Series (JPCS
Budget Processes: Theory and Experimental Evidence
This paper studies budget processes, both theoretically and experimentally. We compare the outcomes of bottom-up and top-down budget processes. It is often presumed that a top-down budget process leads to a smaller overall budget than a bottom-up budget process. Ferejohn and Krehbiel (1987) showed theoretically that this need not be the case. We test experimentally the theoretical predictions of their work. The evidence from these experiments lends strong support to their theory, both at the aggregate and the individual subject level
Dynamic Microscopic Theory of Fusion Using DC-TDHF
The density-constrained time-dependent Hartree-Fock (DC-TDHF) theory is a
fully microscopic approach for calculating heavy-ion interaction potentials and
fusion cross sections below and above the fusion barrier. We discuss recent
applications of DC-TDHF method to fusion of light and heavy systems.Comment: Proceedings for the talk presented by A.S. Umar at the Nuclear
Structure and Dynamics II, Opatija, Croatia, July 9-13, 201
WDR19 : An ancient, retrograde, intraflagellar ciliary protein is mutated in autosomal recessive retinitis pigmentosa and in SeniorâLoken syndrome
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99013/1/cge12196.pd
Incomplete Punishment Networks in Public Goods Games: Experimental Evidence
Abundant evidence suggests that high levels of contributions to public goods can be sustained through self-governed monitoring and sanctioning. This experimental study investigates the effectiveness of decentralized sanctioning institutions in alternative punishment networks. Our results show that the structure of punishment network significantly affects allocations to the public good. In addition, we observe that network configurations are more important than punishment capacities for the levels of public good provision, imposed sanctions and economic efficiency. Lastly, we show that targeted revenge is a major driver of anti-social punishment
Fucosylated AGP glycopeptides as biomarkers of HNF1A-Maturity onset diabetes of the young
Aims: We previously demonstrated that antennary fucosylated N-glycans on plasma proteins are regulated by HNF1A and can identify cases of Maturity-Onset Diabetes of the Young caused by HNF1A variants (HNF1A-MODY). Based on literature data, we further postulated that N-glycans with best diagnostic value mostly originate from alpha-1-acid glycoprotein (AGP). In this study we analyzed fucosylation of AGP in subjects with HNF1A-MODY and other types of diabetes aiming to evaluate its diagnostic potential.
Methods: A recently developed LC-MS method for AGP N-glycopeptide analysis was utilized in two independent cohorts: a) 466 subjects with different diabetes subtypes to test the fucosylation differences, b) 98 selected individuals to test the discriminative potential for pathogenic HNF1A variants.
Results: Our results showed significant reduction in AGP fucosylation associated to HNF1A-MODY when compared to other diabetes subtypes. Additionally, ROC curve analysis confirmed significant discriminatory potential of individual fucosylated AGP glycopeptides, where the best performing glycopeptide had an AUC of 0.94 (95% CI 0.90â0.99).
Conclusions: A glycopeptide based diagnostic tool would be beneficial for patient stratification by providing information about the functionality of HNF1A. It could assist the interpretation of DNA sequencing results and be a useful addition to the differential diagnostic process.publishedVersio
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